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A cell-based high-throughput screening assay system for inhibitor compounds of antigen presentation by HLA class II molecule
A number of autoimmune diseases are associated with the genotypes of human leukocyte antigen class II (HLA), some of which present peptides derived from self-proteins, resulting in clonal expansion of self-reactive T cells. Therefore, selective inhibition of self-peptide loading onto such disease-as...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5533769/ https://ncbi.nlm.nih.gov/pubmed/28754892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07080-4 |
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