Sepsis induces incomplete M2 phenotype polarization in peritoneal exudate cells in mice

BACKGROUND: Macrophages can differentiate into pro-inflammatory (M1) or anti-inflammatory (M2) phenotypes upon exposure to a pathogen or a cytokine microenvironment. However, M1/M2 macrophage polarization in polymicrobial sepsis has not been fully characterized. METHODS: The polarity of peritoneal e...

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Udgivet i:J Intensive Care
Main Authors: Watanabe, Nobuo, Suzuki, Yusuke, Inokuchi, Sadaki, Inoue, Shigeaki
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4709882/
https://ncbi.nlm.nih.gov/pubmed/26759721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40560-015-0124-1
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