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Salt Bridge Formation between the I-BAR Domain and Lipids Increases Lipid Density and Membrane Curvature
The BAR domain superfamily proteins sense or induce curvature in membranes. The inverse-BAR domain (I-BAR) is a BAR domain that forms a straight “zeppelin-shaped” dimer. The mechanisms by which IRSp53 I-BAR binds to and deforms a lipid membrane are investigated here by all-atom molecular dynamics si...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5533756/ https://ncbi.nlm.nih.gov/pubmed/28754893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06334-5 |
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