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Mechanism of endophilin N-BAR domain-mediated membrane curvature

Endophilin-A1 is a BAR domain-containing protein enriched at synapses and is implicated in synaptic vesicle endocytosis. It binds to dynamin and synaptojanin via a C-terminal SH3 domain. We examine the mechanism by which the BAR domain and an N-terminal amphipathic helix, which folds upon membrane b...

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Bibliografiske detaljer
Main Authors: Gallop, Jennifer L, Jao, Christine C, Kent, Helen M, Butler, P Jonathan G, Evans, Philip R, Langen, Ralf, McMahon, Harvey T
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1500843/
https://ncbi.nlm.nih.gov/pubmed/16763559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601174
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