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Intein Zymogens: Conditional Assembly and Splicing of Split Inteins via Targeted Proteolysis

[Image: see text] Naturally split inteins have found widespread use in chemical biology due to their ability to drive the ligation of separately expressed polypeptides through a process termed protein trans-splicing (PTS). In this study, we harness PTS by rendering association of split intein fragme...

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Bibliografische gegevens
Gepubliceerd in:J Am Chem Soc
Hoofdauteurs: Gramespacher, Josef A., Stevens, Adam J., Nguyen, Duy P., Chin, Jason W., Muir, Tom W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2017
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533455/
https://ncbi.nlm.nih.gov/pubmed/28562027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b02618
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