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Solution NMR structure of the TRIM21 B-box2 and identification of residues involved in its interaction with the RING domain
Tripartite motif-containing (TRIM) proteins are defined by the sequential arrangement of RING, B-box and coiled-coil domains (RBCC), where the B-box domain is a unique feature of the TRIM protein family. TRIM21 is an E3 ubiquitin-protein ligase implicated in innate immune signaling by acting as an a...
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| Pubblicato in: | PLoS One |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5533445/ https://ncbi.nlm.nih.gov/pubmed/28753623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181551 |
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