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The origin of the PB1 segment of swine influenza A virus subtype H1N2 determines viral pathogenicity in mice

Swine appear to be a key species in the generation of novel human influenza pandemics. Previous pandemic viruses are postulated to have evolved in swine by reassortment of avian, human, and swine influenza viruses. The human pandemic influenza viruses that emerged in 1957 and 1968 as well as swine v...

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Bibliographic Details
Published in:Virus Res
Main Authors: Metreveli, Giorgi, Gao, Qinshan, Mena, Nacho, Schmolke, Mirco, Berg, Mikael, Albrecht, Randy A., García-Sastre, Adolfo
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533274/
https://ncbi.nlm.nih.gov/pubmed/24726997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2014.03.023
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