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Nicotinamide Mononucleotide, an NAD(+) Precursor, Rescues Age-Associated Susceptibility to AKI in a Sirtuin 1–Dependent Manner

The rapid growth of an aging population creates challenges regarding age-related diseases, including AKI, for which both the prevalence and death rate increase with age. The molecular mechanism by which the aged kidney becomes more susceptible to acute injury has not been completely elucidated. In t...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Guan, Yi, Wang, Su-Rong, Huang, Xin-Zhong, Xie, Qiong-hong, Xu, Yun-Yu, Shang, Da, Hao, Chuan-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533221/
https://ncbi.nlm.nih.gov/pubmed/28246130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016040385
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