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Tomoregulin (TMEFF2) Binds Alzheimer’s Disease Amyloid-β (Aβ) Oligomer and AβPP and Protects Neurons from Aβ-Induced Toxicity

Amyloid-β (Aβ) protein causes neurotoxicity and its abnormal aggregation into amyloid is a pathological hallmark of Alzheimer’s disease (AD). Cellular proteins able to interact with Aβ or its precursor, AβPP (amyloid-β protein precursor), may regulate Aβ production and neurotoxicity. We identified a...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Hong, Hyun-Seok, Maezawa, Izumi, Petrlova, Jitka, Zhao, Xiao-Yan, Voss, John C., Jin, Lee-Way
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533101/
https://ncbi.nlm.nih.gov/pubmed/26402097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-150318
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