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Rett Syndrome Microglia Damage Dendrites and Synapses by the Elevated Release of Glutamate
MECP2, an X-linked gene encoding the epigenetic factor methyl-CpG-binding protein-2, is mutated in Rett syndrome (RTT) and aberrantly expressed in autism. Most children affected by RTT are heterozygous Mecp2(−/+) females whose brain function is impaired postnatally due to MeCP2 deficiency. Recent st...
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| Publicado no: | J Neurosci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5533099/ https://ncbi.nlm.nih.gov/pubmed/20392956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5966-09.2010 |
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