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CX(3)CR1 ablation ameliorates motor and respiratory dysfunctions and improves survival of a Rett syndrome mouse model
Rett syndrome (RTT) is a neurodevelopmental disorder caused by loss-of-function mutations in the gene encoding MeCP2, an epigenetic modulator that binds the methyl CpG dinucleotide in target genes to regulate transcription. Previously we and others reported a role of microglia in the pathophysiology...
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| Veröffentlicht in: | Brain Behav Immun |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5531048/ https://ncbi.nlm.nih.gov/pubmed/26883520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2016.02.014 |
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