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Rett Syndrome Astrocytes Are Abnormal and Spread MeCP2 Deficiency through Gap Junctions
MECP2, an X-linked gene encoding the epigenetic factor methyl-CpG-binding protein-2, is mutated in Rett syndrome (RTT) and aberrantly expressed in autism. Most children affected by RTT are heterozygous Mecp2 (−/+) females whose brain function is impaired postnatally due to MeCP2 deficiency. While pr...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Society for Neuroscience
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3436907/ https://ncbi.nlm.nih.gov/pubmed/19386901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0324-09.2009 |
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