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Improved Synthesis for Modular Ascarosides Uncovers Biological Activity
A versatile synthesis of modular ascarosides, a family of signaling molecules from Caenorhabditis elegans and other nematodes, via hydrogenolysis of a cyclic sulfate derived from methyl-α-l-rhamnopyranoside is reported. The route enables selective introduction of different side chains at the 1, 2, a...
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| Publicado no: | Org Lett |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5533076/ https://ncbi.nlm.nih.gov/pubmed/28513161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b01009 |
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