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Comparative Metabolomics Reveals Biogenesis of Ascarosides, a Modular Library of Small-Molecule Signals in C. elegans

In the model organism Caenorhabditis elegans, a family of endogenous small molecules, the ascarosides, function as key regulators of developmental timing and behavior that act upstream of conserved signaling pathways. The ascarosides are based on the dideoxysugar ascarylose, which is linked to fatty...

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Main Authors: von Reuss, Stephan H., Bose, Neelanjan, Srinivasan, Jagan, Yim, Joshua J., Judkins, Joshua C., Sternberg, Paul W., Schroeder, Frank C.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269134/
https://ncbi.nlm.nih.gov/pubmed/22239548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja210202y
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