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Microsatellite instability regulates transcription factor binding and gene expression

Microsatellites are tandemly repeated simple sequence DNA motifs widely prevalent in eukaryotic and prokaryotic genomes. In pathogenic bacteria, instability of these hypermutable loci through slipped-strand mispairing mediates the high-frequency reversible switching of phenotype expression, i.e., ph...

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Detalhes bibliográficos
Main Authors: Martin, Patricia, Makepeace, Katherine, Hill, Stuart A., Hood, Derek W., Moxon, E. Richard
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC553301/
https://ncbi.nlm.nih.gov/pubmed/15728391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406805102
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