Neisseria meningitidis Escape from the Bactericidal Activity of a Monoclonal Antibody Is Mediated by Phase Variation of lgtG and Enhanced by a Mutator Phenotype

Bacteria adapt to environmental changes through high-frequency switches in expression of specific phenotypes. Localized hypermutation mediated by simple sequence repeats is an important mechanism of such phase variation (PV) in Neisseria meningitidis. Loss or gain of nucleotides in a poly(C) tract l...

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Detalhes bibliográficos
Main Authors: Bayliss, Christopher D., Hoe, J. Claire, Makepeace, Katherine, Martin, Patricia, Hood, Derek W., Moxon, E. Richard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573340/
https://ncbi.nlm.nih.gov/pubmed/18694967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00395-08
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