Monocrotaline Induces Endothelial Injury and Pulmonary Hypertension by Targeting the Extracellular Calcium–Sensing Receptor

BACKGROUND: Monocrotaline has been widely used to establish an animal model of pulmonary hypertension. The molecular target underlying monocrotaline‐induced pulmonary artery endothelial injury and pulmonary hypertension remains unknown. The extracellular calcium–sensing receptor (CaSR) and particula...

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Dades bibliogràfiques
Publicat a:J Am Heart Assoc
Autors principals: Xiao, Rui, Su, Yuan, Feng, Tian, Sun, Mengxiang, Liu, Bingxun, Zhang, Jiwei, Lu, Yankai, Li, Jiansha, Wang, Tao, Zhu, Liping, Hu, Qinghua
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533002/
https://ncbi.nlm.nih.gov/pubmed/28330842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.004865
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