Monocrotaline Induces Endothelial Injury and Pulmonary Hypertension by Targeting the Extracellular Calcium–Sensing Receptor

BACKGROUND: Monocrotaline has been widely used to establish an animal model of pulmonary hypertension. The molecular target underlying monocrotaline‐induced pulmonary artery endothelial injury and pulmonary hypertension remains unknown. The extracellular calcium–sensing receptor (CaSR) and particula...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Xiao, Rui, Su, Yuan, Feng, Tian, Sun, Mengxiang, Liu, Bingxun, Zhang, Jiwei, Lu, Yankai, Li, Jiansha, Wang, Tao, Zhu, Liping, Hu, Qinghua
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533002/
https://ncbi.nlm.nih.gov/pubmed/28330842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.004865
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