Monocrotaline Induces Endothelial Injury and Pulmonary Hypertension by Targeting the Extracellular Calcium–Sensing Receptor

BACKGROUND: Monocrotaline has been widely used to establish an animal model of pulmonary hypertension. The molecular target underlying monocrotaline‐induced pulmonary artery endothelial injury and pulmonary hypertension remains unknown. The extracellular calcium–sensing receptor (CaSR) and particula...

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Dettagli Bibliografici
Pubblicato in:J Am Heart Assoc
Autori principali: Xiao, Rui, Su, Yuan, Feng, Tian, Sun, Mengxiang, Liu, Bingxun, Zhang, Jiwei, Lu, Yankai, Li, Jiansha, Wang, Tao, Zhu, Liping, Hu, Qinghua
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533002/
https://ncbi.nlm.nih.gov/pubmed/28330842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.004865
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