Mechanistic Investigation of the Specific Anticancer Property of Artemisinin and Its Combination with Aminolevulinic Acid for Enhanced Anticolorectal Cancer Activity

[Image: see text] The antimalarial artemisinin (ART) possesses anticancer activity, but its underlying mechanism remains largely unclear. Using a chemical proteomics approach with artemisinin-based activity probes, we identified over 300 specific ART targets. This reveals an anticancer mechanism whe...

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Gepubliceerd in:ACS Cent Sci
Hoofdauteurs: Wang, Jigang, Zhang, Jianbin, Shi, Yin, Xu, Chengchao, Zhang, Chongjing, Wong, Yin Kwan, Lee, Yew Mun, Krishna, Sanjeev, He, Yingke, Lim, Teck Kwang, Sim, Weiying, Hua, Zi-Chun, Shen, Han-Ming, Lin, Qingsong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2017
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5532725/
https://ncbi.nlm.nih.gov/pubmed/28776016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.7b00156
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