α-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABA(B) receptors

OBJECTIVE: α-Conotoxin Vc1.1 is a small disulfide-bonded peptide from the venom of the marine cone snail Conus victoriae. Vc1.1 has antinociceptive actions in animal models of neuropathic pain, but its applicability to inhibiting human dorsal root ganglion (DRG) neuroexcitability and reducing chroni...

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Detaylı Bibliyografya
Yayımlandı:Gut
Asıl Yazarlar: Castro, Joel, Harrington, Andrea M, Garcia-Caraballo, Sonia, Maddern, Jessica, Grundy, Luke, Zhang, Jingming, Page, Guy, Miller, Paul E, Craik, David J, Adams, David J, Brierley, Stuart M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMJ Publishing Group 2017
Konular:
Neurogastroenterology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5532460/
https://ncbi.nlm.nih.gov/pubmed/26887818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2015-310971
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