α-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABA(B) receptors

OBJECTIVE: α-Conotoxin Vc1.1 is a small disulfide-bonded peptide from the venom of the marine cone snail Conus victoriae. Vc1.1 has antinociceptive actions in animal models of neuropathic pain, but its applicability to inhibiting human dorsal root ganglion (DRG) neuroexcitability and reducing chroni...

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Dades bibliogràfiques
Publicat a:Gut
Autors principals: Castro, Joel, Harrington, Andrea M, Garcia-Caraballo, Sonia, Maddern, Jessica, Grundy, Luke, Zhang, Jingming, Page, Guy, Miller, Paul E, Craik, David J, Adams, David J, Brierley, Stuart M
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 2017
Matèries:
Neurogastroenterology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5532460/
https://ncbi.nlm.nih.gov/pubmed/26887818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2015-310971
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