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Tannic acid as a plant-derived polyphenol exerts vasoprotection via enhancing KLF2 expression in endothelial cells

The transcription factor Kruppel-like factor 2 (KLF2) is a critical anti-inflammatory and anti-atherogenic molecule in vascular endothelium. Enhancing KLF2 expression and activity improves endothelial function and prevents atherosclerosis. However, the pharmacological and molecular regulators for KL...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Xu, Yanni, Liu, Peng, Xu, Suowen, Koroleva, Marina, Zhang, Shuya, Si, Shuyi, Jin, Zheng Gen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5532219/
https://ncbi.nlm.nih.gov/pubmed/28751752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06803-x
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