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Activation of SIRT1 by resveratrol induces KLF2 expression conferring an endothelial vasoprotective phenotype
AIMS: Resveratrol activates Sirtuin 1 (SIRT1), a nicotinamide adenine dinucleotide-dependent deacetylase which modulates metabolic homeostasis and improves several pathophysiological features present in diseases of ageing. In particular, it has been shown that SIRT1 activation improves endothelial d...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2802207/ https://ncbi.nlm.nih.gov/pubmed/19815564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvp337 |
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