Activation of SIRT1 by resveratrol induces KLF2 expression conferring an endothelial vasoprotective phenotype

AIMS: Resveratrol activates Sirtuin 1 (SIRT1), a nicotinamide adenine dinucleotide-dependent deacetylase which modulates metabolic homeostasis and improves several pathophysiological features present in diseases of ageing. In particular, it has been shown that SIRT1 activation improves endothelial d...

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Hauptverfasser: Gracia-Sancho, Jorge, Villarreal, Guadalupe, Zhang, Yuzhi, García-Cardeña, Guillermo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2010
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802207/
https://ncbi.nlm.nih.gov/pubmed/19815564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvp337
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