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An activator of an adenylation domain revealed by activity but not sequence homology
Nonribosomal peptide synthetases (NRPSs), responsible for synthesizing many medicinally important natural products, frequently use adenylation domain activators (ADAs) to promote substrate loading. Although ADAs are usually MbtH-like proteins (MLPs), a new type of ADA appears to promote an NRPS-depe...
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| Publicado no: | Chembiochem |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5531763/ https://ncbi.nlm.nih.gov/pubmed/27447757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201600291 |
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