Low calcium diet increases 4T1 mammary tumor carcinoma cell burden and bone pathology in mice

Breast cancer metastasizes to bone in the majority of patients with advanced disease. We investigated the effects of inadequate dietary calcium (Ca) on bone turnover, tumor growth, and bone response to tumor in tibia inoculated with 4T1 mammary carcinoma cells. Nine-month-old female Balb/c mice were...

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Veröffentlicht in:PLoS One
Hauptverfasser: Wang, Wendan, Gordon, Jody L., Philbrick, Kenneth A., Yang, Xujuan, Branscum, Adam J., Löhr, Christiane V., Haschek, Wanda M., Turner, Russell T., Iwaniec, Urszula T., Helferich, William G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531562/
https://ncbi.nlm.nih.gov/pubmed/28750038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180886
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