Astrocytic tight junctions control inflammatory CNS lesion pathogenesis

Lesions and neurologic disability in inflammatory CNS diseases such as multiple sclerosis (MS) result from the translocation of leukocytes and humoral factors from the vasculature, first across the endothelial blood-brain barrier (BBB) and then across the astrocytic glia limitans (GL). Factors secre...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Horng, Sam, Therattil, Anthony, Moyon, Sarah, Gordon, Alexandra, Kim, Karla, Argaw, Azeb Tadesse, Hara, Yuko, Mariani, John N., Sawai, Setsu, Flodby, Per, Crandall, Edward D., Borok, Zea, Sofroniew, Michael V., Chapouly, Candice, John, Gareth R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531407/
https://ncbi.nlm.nih.gov/pubmed/28737509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI91301
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