Gentamicin induces functional type VII collagen in recessive dystrophic epidermolysis bullosa patients

BACKGROUND. Recessive dystrophic epidermolysis bullosa (RDEB) is an incurable disease caused by mutations in the gene encoding type VII collagen, the major component of anchoring fibrils (AF). We previously demonstrated that gentamicin produced functional type VII collagen in RDEB cells harboring no...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Clin Invest
Prif Awduron: Woodley, David T., Cogan, Jon, Hou, Yingping, Lyu, Chao, Marinkovich, M. Peter, Keene, Douglas, Chen, Mei
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2017
Pynciau:
Clinical Medicine
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531396/
https://ncbi.nlm.nih.gov/pubmed/28691931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI92707
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg