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Gentamicin induces functional type VII collagen in recessive dystrophic epidermolysis bullosa patients

BACKGROUND. Recessive dystrophic epidermolysis bullosa (RDEB) is an incurable disease caused by mutations in the gene encoding type VII collagen, the major component of anchoring fibrils (AF). We previously demonstrated that gentamicin produced functional type VII collagen in RDEB cells harboring no...

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Опубликовано в: :J Clin Invest
Главные авторы: Woodley, David T., Cogan, Jon, Hou, Yingping, Lyu, Chao, Marinkovich, M. Peter, Keene, Douglas, Chen, Mei
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531396/
https://ncbi.nlm.nih.gov/pubmed/28691931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI92707
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