Hepatic β-arrestin 2 is essential for maintaining euglycemia

An increase in hepatic glucose production (HGP) represents a key feature of type 2 diabetes. This deficiency in metabolic control of glucose production critically depends on enhanced signaling through hepatic glucagon receptors (GCGRs). Here, we have demonstrated that selective inactivation of the G...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Zhu, Lu, Rossi, Mario, Cui, Yinghong, Lee, Regina J., Sakamoto, Wataru, Perry, Nicole A., Urs, Nikhil M., Caron, Marc G., Gurevich, Vsevolod V., Godlewski, Grzegorz, Kunos, George, Chen, Minyong, Chen, Wei, Wess, Jürgen
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2017
Sujets:
Brief Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531395/
https://ncbi.nlm.nih.gov/pubmed/28650340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI92913
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires