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Modifications of tau protein after cerebral ischemia and reperfusion in rats are similar to those occurring in Alzheimer’s disease – Hyperphosphorylation and cleavage of 4- and 3-repeat tau

Epidemiological studies have suggested a close relationship between cerebral ischemia and Alzheimer’s disease (AD). To clarify the pathological association of tau dynamics in both diseases, we performed comprehensive studies on the posttranslational modification of tau in cerebral ischemia and reper...

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Bibliografiske detaljer
Udgivet i:J Cereb Blood Flow Metab
Main Authors: Fujii, Hiroki, Takahashi, Tetsuya, Mukai, Tomoya, Tanaka, Shigeru, Hosomi, Naohisa, Maruyama, Hirofumi, Sakai, Norio, Matsumoto, Masayasu
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531343/
https://ncbi.nlm.nih.gov/pubmed/27629097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X16668889
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