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Sphingomyelin encrypts tissue factor: ATP-induced activation of A-SMase leads to tissue factor decryption and microvesicle shedding

A majority of tissue factor (TF) on cell surfaces exists in an encrypted state with minimal to no procoagulant activity. At present, it is unclear whether limited availability of phosphatidylserine (PS) and/or a specific membrane lipid in the outer leaflet of the plasma membrane contributes to TF en...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Blood Adv
Päätekijät: Wang, Jue, Pendurthi, Usha R., Rao, L. Vijaya Mohan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531194/
https://ncbi.nlm.nih.gov/pubmed/28758160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2016003947
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