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Sphingomyelin encrypts tissue factor: ATP-induced activation of A-SMase leads to tissue factor decryption and microvesicle shedding

A majority of tissue factor (TF) on cell surfaces exists in an encrypted state with minimal to no procoagulant activity. At present, it is unclear whether limited availability of phosphatidylserine (PS) and/or a specific membrane lipid in the outer leaflet of the plasma membrane contributes to TF en...

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Bibliografski detalji
Izdano u:Blood Adv
Glavni autori: Wang, Jue, Pendurthi, Usha R., Rao, L. Vijaya Mohan
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531194/
https://ncbi.nlm.nih.gov/pubmed/28758160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2016003947
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