IFITM1 suppression blocks proliferation and invasion of aromatase inhibitor-resistant breast cancer in vivo by JAK/STAT-mediated induction of p21

Interferon induced transmembrane protein 1 (IFITM1) belongs to a family of interferon stimulated genes (ISGs) that is associated with tumor progression and DNA damage resistance, however, its role in endocrine resistance is not known. Here, we correlate IFITM1 expression with clinical stage and poor...

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發表在:Cancer Lett
Main Authors: Lui, Asona J., Geanes, Eric S., Ogony, Joshua, Behbod, Fariba, Marquess, Jordan, Valdez, Kelli, Jewell, William, Tawfik, Ossama, Lewis-Wambi, Joan
格式: Artigo
語言:Inglês
出版: 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530765/
https://ncbi.nlm.nih.gov/pubmed/28411130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2017.04.005
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