IFITM1 suppression blocks proliferation and invasion of aromatase inhibitor-resistant breast cancer in vivo by JAK/STAT-mediated induction of p21

Interferon induced transmembrane protein 1 (IFITM1) belongs to a family of interferon stimulated genes (ISGs) that is associated with tumor progression and DNA damage resistance, however, its role in endocrine resistance is not known. Here, we correlate IFITM1 expression with clinical stage and poor...

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Bibliographic Details
Published in:Cancer Lett
Main Authors: Lui, Asona J., Geanes, Eric S., Ogony, Joshua, Behbod, Fariba, Marquess, Jordan, Valdez, Kelli, Jewell, William, Tawfik, Ossama, Lewis-Wambi, Joan
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530765/
https://ncbi.nlm.nih.gov/pubmed/28411130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2017.04.005
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