IFITM1 suppression blocks proliferation and invasion of aromatase inhibitor-resistant breast cancer in vivo by JAK/STAT-mediated induction of p21

Interferon induced transmembrane protein 1 (IFITM1) belongs to a family of interferon stimulated genes (ISGs) that is associated with tumor progression and DNA damage resistance, however, its role in endocrine resistance is not known. Here, we correlate IFITM1 expression with clinical stage and poor...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cancer Lett
Auteurs principaux: Lui, Asona J., Geanes, Eric S., Ogony, Joshua, Behbod, Fariba, Marquess, Jordan, Valdez, Kelli, Jewell, William, Tawfik, Ossama, Lewis-Wambi, Joan
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530765/
https://ncbi.nlm.nih.gov/pubmed/28411130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2017.04.005
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