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(11)C-Labeling of Aryl Ketones as Candidate Histamine Subtype-3 Receptor PET Radioligands through Pd(0)-Mediated (11)C-Carbonylative Coupling

Pd(0)-mediated coupling between iodoarenes, [(11)C]carbon monoxide and aryltributylstannanes has been used to prepare simple model [(11)C]aryl ketones. Here, we aimed to label four 2-aminoethylbenzofuran chemotype based molecules ([(11)C]1–4) in the carbonyl position, as prospective positron emissio...

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Detalles Bibliográficos
Publicado en:Molecules
Autores principales: Siméon, Fabrice G., Culligan, William J., Lu, Shuiyu, Pike, Victor W.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530730/
https://ncbi.nlm.nih.gov/pubmed/28498336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22050792
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