Wnt signalling modulates transcribed-ultraconserved regions in hepatobiliary cancers

OBJECTIVE: Transcribed-ultraconserved regions (T-UCR) are long non-coding RNAs which are conserved across species and are involved in carcinogenesis. We studied T-UCRs downstream of the Wnt/β-catenin pathway in liver cancer. DESIGN: Hypomorphic Apc mice (Apcfl/fl) and thiocetamide (TAA)-treated rats...

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Détails bibliographiques
Publié dans:Gut
Auteurs principaux: Carotenuto, Pietro, Fassan, Matteo, Pandolfo, Rosantony, Lampis, Andrea, Vicentini, Caterina, Cascione, Luciano, Paulus-Hock, Viola, Boulter, Luke, Guest, Rachel, Quagliata, Luca, Hahne, Jens Claus, Ridgway, Rachel, Jamieson, Tam, Athineos, Dimitris, Veronese, Angelo, Visone, Rosa, Murgia, Claudio, Ferrari, Giulia, Guzzardo, Vincenza, Evans, Thomas Ronald Jeffry, MacLeod, Martin, Feng, Gui Ji, Dale, Trevor, Negrini, Massimo, Forbes, Stuart J, Terracciano, Luigi, Scarpa, Aldo, Patel, Tushar, Valeri, Nicola, Workman, Paul, Sansom, Owen, Braconi, Chiara
Format: Artigo
Langue:Inglês
Publié: BMJ Publishing Group 2017
Sujets:
GI cancer
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530482/
https://ncbi.nlm.nih.gov/pubmed/27618837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2016-312278
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