Wnt signalling modulates transcribed-ultraconserved regions in hepatobiliary cancers

OBJECTIVE: Transcribed-ultraconserved regions (T-UCR) are long non-coding RNAs which are conserved across species and are involved in carcinogenesis. We studied T-UCRs downstream of the Wnt/β-catenin pathway in liver cancer. DESIGN: Hypomorphic Apc mice (Apcfl/fl) and thiocetamide (TAA)-treated rats...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Carotenuto, Pietro, Fassan, Matteo, Pandolfo, Rosantony, Lampis, Andrea, Vicentini, Caterina, Cascione, Luciano, Paulus-Hock, Viola, Boulter, Luke, Guest, Rachel, Quagliata, Luca, Hahne, Jens Claus, Ridgway, Rachel, Jamieson, Tam, Athineos, Dimitris, Veronese, Angelo, Visone, Rosa, Murgia, Claudio, Ferrari, Giulia, Guzzardo, Vincenza, Evans, Thomas Ronald Jeffry, MacLeod, Martin, Feng, Gui Ji, Dale, Trevor, Negrini, Massimo, Forbes, Stuart J, Terracciano, Luigi, Scarpa, Aldo, Patel, Tushar, Valeri, Nicola, Workman, Paul, Sansom, Owen, Braconi, Chiara
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2017
Assuntos:
GI cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530482/
https://ncbi.nlm.nih.gov/pubmed/27618837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2016-312278
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