Wnt signalling modulates transcribed-ultraconserved regions in hepatobiliary cancers

OBJECTIVE: Transcribed-ultraconserved regions (T-UCR) are long non-coding RNAs which are conserved across species and are involved in carcinogenesis. We studied T-UCRs downstream of the Wnt/β-catenin pathway in liver cancer. DESIGN: Hypomorphic Apc mice (Apcfl/fl) and thiocetamide (TAA)-treated rats...

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Dettagli Bibliografici
Pubblicato in:Gut
Autori principali: Carotenuto, Pietro, Fassan, Matteo, Pandolfo, Rosantony, Lampis, Andrea, Vicentini, Caterina, Cascione, Luciano, Paulus-Hock, Viola, Boulter, Luke, Guest, Rachel, Quagliata, Luca, Hahne, Jens Claus, Ridgway, Rachel, Jamieson, Tam, Athineos, Dimitris, Veronese, Angelo, Visone, Rosa, Murgia, Claudio, Ferrari, Giulia, Guzzardo, Vincenza, Evans, Thomas Ronald Jeffry, MacLeod, Martin, Feng, Gui Ji, Dale, Trevor, Negrini, Massimo, Forbes, Stuart J, Terracciano, Luigi, Scarpa, Aldo, Patel, Tushar, Valeri, Nicola, Workman, Paul, Sansom, Owen, Braconi, Chiara
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2017
Soggetti:
GI cancer
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530482/
https://ncbi.nlm.nih.gov/pubmed/27618837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2016-312278
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