Tocilizumab combination therapy or monotherapy or methotrexate monotherapy in methotrexate-naive patients with early rheumatoid arthritis: 2-year clinical and radiographic results from the randomised, placebo-controlled FUNCTION trial

OBJECTIVE: Investigate whether the efficacy and safety of intravenous tocilizumab (TCZ) demonstrated at week 52 in patients with early rheumatoid arthritis (RA) are maintained to week 104. METHODS: Methotrexate (MTX)-naive patients with early progressive RA were randomly assigned to double-blind 4 m...

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Podrobná bibliografie
Vydáno v:Ann Rheum Dis
Hlavní autoři: Burmester, Gerd R, Rigby, William F, van Vollenhoven, Ronald F, Kay, Jonathan, Rubbert-Roth, Andrea, Blanco, Ricardo, Kadva, Alysha, Dimonaco, Sophie
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2017
Témata:
Clinical and Epidemiological Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530348/
https://ncbi.nlm.nih.gov/pubmed/28389552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2016-210561
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