Filgotinib in combination with methotrexate or as monotherapy versus methotrexate monotherapy in patients with active rheumatoid arthritis and limited or no prior exposure to methotrexate: the phase 3, randomised controlled FINCH 3 trial

OBJECTIVES: To investigate efficacy and safety of the Janus kinase-1 inhibitor filgotinib in patients with active rheumatoid arthritis (RA) with limited or no prior methotrexate (MTX) exposure. METHODS: This 52-week, phase 3, multicentre, double-blind clinical trial (NCT02886728) evaluated once-dail...

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Publicat a:Ann Rheum Dis
Autors principals: Westhovens, René, Rigby, William F C, van der Heijde, Désirée, Ching, Daniel W T, Stohl, William, Kay, Jonathan, Chopra, Arvind, Bartok, Beatrix, Matzkies, Franziska, Yin, Zhaoyu, Guo, Ying, Tasset, Chantal, Sundy, John S, Jahreis, Angelika, Mozaffarian, Neelufar, Messina, Osvaldo Daniel, Landewé, Robert BM, Atsumi, Tatsuya, Burmester, Gerd R
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 2021
Matèries:
Rheumatoid Arthritis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8142453/
https://ncbi.nlm.nih.gov/pubmed/33452004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2020-219213
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