Nalaganje...

Molecular dynamics simulation analysis of the effect of T790M mutation on epidermal growth factor receptor protein architecture in non-small cell lung carcinoma

Non-small cell lung cancer etiology and its treatment failure are due to epidermal growth factor receptor (EGFR) kinase domain mutations at amino acid position 790. The mutational change from threonine to methionine at position 790 (T790M) is responsible for tyrosine kinase inhibition failure. Using...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncol Lett
Main Authors: Peng, Xiao-Nu, Wang, Jing, Zhang, Wei
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530049/
https://ncbi.nlm.nih.gov/pubmed/28789446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6387
Oznake: Označite
Brez oznak, prvi označite!