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In silico insight into EGFR treatment in patients with lung carcinoma and T790M mutations

The T790M mutational basis of treatment failure, following treatment via alteration of the epidermal growth factor receptor (EGFR) pathway, is a well-known anomaly in patients with non-small cell lung cancer (NSCLC). The T790M mutation activates the kinase domain, causing tyrosine kinase inhibitors,...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Zang, Shu-Zhi, Yang, Yan-Rong, Zhao, Sha-Sha, Li, Yun-Xia, Gao, Xin-Yuan, Zhong, Chun-Lei
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5443239/
https://ncbi.nlm.nih.gov/pubmed/28565760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.4168
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