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In silico insight into EGFR treatment in patients with lung carcinoma and T790M mutations

The T790M mutational basis of treatment failure, following treatment via alteration of the epidermal growth factor receptor (EGFR) pathway, is a well-known anomaly in patients with non-small cell lung cancer (NSCLC). The T790M mutation activates the kinase domain, causing tyrosine kinase inhibitors,...

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Publicat a:Exp Ther Med
Autors principals: Zang, Shu-Zhi, Yang, Yan-Rong, Zhao, Sha-Sha, Li, Yun-Xia, Gao, Xin-Yuan, Zhong, Chun-Lei
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5443239/
https://ncbi.nlm.nih.gov/pubmed/28565760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.4168
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