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Development of epidermal growth factor receptor tyrosine kinase inhibitors against EGFR T790M. Mutation in non small-cell lung carcinoma

Individualized therapies targeting epidermal growth factor receptor (EGFR) mutations show promises for the treatment of non small-cell lung carcinoma (NSCLC). However, disease progression almost invariably occurs 1 year after tyrosine kinase inhibitor (TKI) treatment. The most prominent mechanism of...

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Detalhes bibliográficos
Publicado no:Open Med (Wars)
Main Authors: Wang, Yuli, Guo, Zhitao, Li, Yang, Zhou, Qinghua
Formato: Artigo
Idioma:Inglês
Publicado em: De Gruyter Open 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5329801/
https://ncbi.nlm.nih.gov/pubmed/28352770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/med-2016-0014
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