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On the utility of pooling biological samples in microarray experiments

Over 15% of the data sets catalogued in the Gene Expression Omnibus Database involve RNA samples that have been pooled before hybridization. Pooling affects data quality and inference, but the exact effects are not yet known because pooling has not been systematically studied in the context of micro...

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Hauptverfasser: Kendziorski, C., Irizarry, R. A., Chen, K.-S., Haag, J. D., Gould, M. N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC552978/
https://ncbi.nlm.nih.gov/pubmed/15755808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500607102
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