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On the utility of pooling biological samples in microarray experiments

Over 15% of the data sets catalogued in the Gene Expression Omnibus Database involve RNA samples that have been pooled before hybridization. Pooling affects data quality and inference, but the exact effects are not yet known because pooling has not been systematically studied in the context of micro...

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Detalhes bibliográficos
Main Authors: Kendziorski, C., Irizarry, R. A., Chen, K.-S., Haag, J. D., Gould, M. N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC552978/
https://ncbi.nlm.nih.gov/pubmed/15755808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500607102
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