Meiotic and epigenetic defects in Dnmt3L-knockout mouse spermatogenesis

The production of mature germ cells capable of generating totipotent zygotes is a highly specialized and sexually dimorphic process. The transition from diploid primordial germ cell to haploid spermatozoa requires genome-wide reprogramming of DNA methylation, stage- and testis-specific gene expressi...

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Detalhes bibliográficos
Main Authors: Webster, Kylie E., O'Bryan, Moira K., Fletcher, Stephen, Crewther, Pauline E., Aapola, Ulla, Craig, Jeff, Harrison, Dion K., Aung, Hnin, Phutikanit, Nawapen, Lyle, Robert, Meachem, Sarah J., Antonarakis, Stylianos E., de Kretser, David M., Hedger, Mark P., Peterson, Pärt, Carroll, Bernard J., Scott, Hamish S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC552976/
https://ncbi.nlm.nih.gov/pubmed/15753313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500702102
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