Meiotic and epigenetic defects in Dnmt3L-knockout mouse spermatogenesis

The production of mature germ cells capable of generating totipotent zygotes is a highly specialized and sexually dimorphic process. The transition from diploid primordial germ cell to haploid spermatozoa requires genome-wide reprogramming of DNA methylation, stage- and testis-specific gene expressi...

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Главные авторы: Webster, Kylie E., O'Bryan, Moira K., Fletcher, Stephen, Crewther, Pauline E., Aapola, Ulla, Craig, Jeff, Harrison, Dion K., Aung, Hnin, Phutikanit, Nawapen, Lyle, Robert, Meachem, Sarah J., Antonarakis, Stylianos E., de Kretser, David M., Hedger, Mark P., Peterson, Pärt, Carroll, Bernard J., Scott, Hamish S.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2005
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC552976/
https://ncbi.nlm.nih.gov/pubmed/15753313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500702102
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