Meiotic and epigenetic defects in Dnmt3L-knockout mouse spermatogenesis

The production of mature germ cells capable of generating totipotent zygotes is a highly specialized and sexually dimorphic process. The transition from diploid primordial germ cell to haploid spermatozoa requires genome-wide reprogramming of DNA methylation, stage- and testis-specific gene expressi...

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Bibliografiska uppgifter
Huvudupphovsmän: Webster, Kylie E., O'Bryan, Moira K., Fletcher, Stephen, Crewther, Pauline E., Aapola, Ulla, Craig, Jeff, Harrison, Dion K., Aung, Hnin, Phutikanit, Nawapen, Lyle, Robert, Meachem, Sarah J., Antonarakis, Stylianos E., de Kretser, David M., Hedger, Mark P., Peterson, Pärt, Carroll, Bernard J., Scott, Hamish S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2005
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC552976/
https://ncbi.nlm.nih.gov/pubmed/15753313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500702102
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